The Carll Lab is hiring a Post-Doctoral Researcher in Cardiac Pathophysiology to experiment and report on the impacts of environmental stressors, including e-cigarettes, extreme heat, and air pollutants. The post-doc will evaluate cardiac conduction, contraction, and structure, in in vivo mouse models.

Our NIH-funded research tests how vaping impairs cardiovascular function and determines the influence of chemical additives, user age, and autonomic reflexes on these effects. We analyze ECG, blood pressure, echocardiography, and plethysmography signals and perform environmentally-relevant exposures in mouse models to inform the public, clinicians, and regulators. We also investigate how diet, life stages, underlying disease, and genetics, enhance susceptibility to environmental exposures. Beyond this, we test basic mechanisms of cardiac arrhythmias and sudden cardiac death, with particular focus on the role of the autonomic nervous system, and perform human studies (epidemiologic, clinical, and cellular) to enhance the translational value of our in vivo research.

Successful candidates will have a Ph.D. or equivalent, background in physiology, toxicology, pharmacology, environmental health, or a closely related field, and experience with in vivo, ex vivo, and/or in vitro cardiovascular models. A sound track-record of publishing and strong internal motivation are essential. Experience in physiology, large datasets, animal research (injection, surgical implants, organ processing), and statistics are preferred. Familiarity with molecular laboratory techniques (Western, ELISA, and/or qRTPCR) is also valued. The individual will be expected to design, manage, and perform studies, present at national/international meetings, and compose original research articles. We follow the NIH's postdoc salary guidelines.

Interested candidates should submit a cover letter, CV, and three references to [email protected]

Academic Setting: The Carll Laboratory interfaces with an exceptionally collaborative team of talented investigators and trainees focused on environmental cardiology and basic cardiovascular sciences within the Center for Cardiometabolic Science and the Christina Lee Brown Envirome Institute at the University of Louisville. Dr. Carll is an Associate Professor of Physiology in the School of Medicine at the University of Louisville. The University of Louisville is a state-supported research university located in Kentucky’s largest metropolitan area, offering a vibrant urban environment for academic and scientific work. The Health Sciences Center in downtown Louisville’s medical complex hosts the university’s health-related programs and the University of Louisville Hospital, providing strong clinical and translational research opportunities.

Qualifications

• Strong Laboratory Skills relevant to cardiovascular biology, toxicology, and physiology, including experimental design and hands-on bench work.
• Robust research skills, including hypothesis generation, literature review, and project management within biomedical or physiological sciences.
• Foundational knowledge in Physics as applied to cardiovascular systems, hemodynamics, and related biophysical processes.
• Data Analysis skills, including statistical methods, quantitative interpretation of experimental results, and proficiency with relevant software tools (e.g., R, Python, GraphPad Prism).
• Teaching and mentoring skills, with the ability to guide graduate and undergraduate trainees and contribute to academic instruction or journal clubs.
• PhD or equivalent doctoral degree in physiology, toxicology, pharmacology, biomedical sciences, or a related field.
• Strong written and verbal communication skills for publishing, presenting, and collaborative work.
• Ability to work independently and as part of a multidisciplinary team, with strong organizational and time-management capabilities.
• Prior experience with animal models, cardiovascular functional assessments, or toxicology studies is highly beneficial.
• Commitment to ethical research practices, laboratory safety, and continued professional development.